{"id":38,"date":"2023-05-31T11:56:23","date_gmt":"2023-05-31T15:56:23","guid":{"rendered":"https:\/\/ghazani-lab.bwh.harvard.edu\/?page_id=38"},"modified":"2025-09-10T16:58:08","modified_gmt":"2025-09-10T20:58:08","slug":"genomic-equity","status":"publish","type":"page","link":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/genomic-equity\/","title":{"rendered":"PRECISION ONCOLOGY &#038; EQUITY"},"content":{"rendered":"<div data-colibri-id=\"38-c1\" class=\"style-266 style-local-38-c1 position-relative\">\n  <!---->\n  <div data-colibri-component=\"section\" data-colibri-id=\"38-c2\" id=\"reusable-sections\" class=\"h-section h-section-global-spacing d-flex align-items-lg-start align-items-md-start align-items-start style-653 style-local-38-c2 position-relative\">\n    <!---->\n    <!---->\n    <div class=\"h-section-grid-container h-section-fluid-container\">\n      <!---->\n      <div data-colibri-id=\"38-c3\" class=\"h-row-container gutters-row-lg-0 gutters-row-md-0 gutters-row-0 gutters-row-v-lg-0 gutters-row-v-md-0 gutters-row-v-0 style-654 style-local-38-c3 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-0 gutters-col-md-0 gutters-col-0 gutters-col-v-lg-0 gutters-col-v-md-0 gutters-col-v-0\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-655-outer style-local-38-c4-outer\">\n            <div data-colibri-id=\"38-c4\" class=\"d-flex h-flex-basis h-column__inner h-ui-empty-state-container h-px-lg-1 h-px-md-1 h-px-1 v-inner-lg-1 v-inner-md-1 v-inner-1 style-655 style-local-38-c4 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100\">\n                <!---->\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-657-outer style-local-38-c5-outer\">\n            <div data-colibri-id=\"38-c5\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-1 h-px-md-1 h-px-1 v-inner-lg-1 v-inner-md-1 v-inner-1 style-657 style-local-38-c5 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"38-c6\" class=\"h-global-transition-all h-heading style-658 style-local-38-c6 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-658 style-local-38-c6\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">PRECISION ONCOLOGY &amp;\n                      <br>GENOMIC VARIATION<\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n  <div data-colibri-component=\"section\" data-colibri-id=\"38-c11\" id=\"custom\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-663 style-local-38-c11 position-relative\">\n    <!---->\n    <!---->\n    <div class=\"h-section-grid-container h-section-fluid-container\">\n      <!---->\n      <div data-colibri-id=\"38-c12\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-1177 style-local-38-c12 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-1178-outer style-local-38-c13-outer\">\n            <div data-colibri-id=\"38-c13\" class=\"d-flex h-flex-basis h-column__inner h-ui-empty-state-container h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-1178 style-local-38-c13 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100\">\n                <!---->\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-1179-outer style-local-38-c14-outer\">\n            <div data-colibri-id=\"38-c14\" class=\"d-flex h-flex-basis h-column__inner h-ui-empty-state-container h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-1179 style-local-38-c14 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100\">\n                <!---->\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n  <div data-colibri-component=\"section\" data-colibri-id=\"38-c15\" id=\"custom-2\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-666 style-local-38-c15 position-relative\">\n    <!---->\n    <!---->\n    <div class=\"h-section-grid-container h-section-boxed-container\">\n      <!---->\n      <div data-colibri-id=\"38-c16\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-965 style-local-38-c16 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-966-outer style-local-38-c17-outer\">\n            <div data-colibri-id=\"38-c17\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-966 style-local-38-c17 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"38-c18\" class=\"h-text h-text-component style-967 style-local-38-c18 position-relative h-element\">\n                  <!---->\n                  <!---->\n                  <div class=\"\">\n                    <p>The clinical interpretation of genomic variants in disease is contingent upon the accurate assessment of the variant allele frequency in the host population. The availability of genome data is largely skewed, with many subpopulations\n                      underrepresented in genome databases. Working with collaborators worldwide, we are investigating genome variations in diverse populations and their role in cancer while creating aggregate databases to make these data broadly accessible.\n                      By developing computational platforms with public web-based access, we are making these diverse datasets accessible to enhance their utility in patient care and genomic medicine.<\/p>\n                    <p>\n                      <br>\n                    <\/p>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>PRECISION ONCOLOGY &amp; GENOMIC VARIATION The clinical interpretation of genomic variants in disease is contingent upon the accurate assessment of the variant allele frequency in the host population. The availability of genome data is largely skewed, with many subpopulations underrepresented in genome databases. Working with collaborators worldwide, we are investigating genome variations in diverse populations [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/full-width-page.php","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-38","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/pages\/38","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/comments?post=38"}],"version-history":[{"count":20,"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/pages\/38\/revisions"}],"predecessor-version":[{"id":3943,"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/pages\/38\/revisions\/3943"}],"wp:attachment":[{"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/media?parent=38"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}