{"id":36,"date":"2023-05-31T11:56:06","date_gmt":"2023-05-31T15:56:06","guid":{"rendered":"https:\/\/ghazani-lab.bwh.harvard.edu\/?page_id=36"},"modified":"2025-09-10T16:57:03","modified_gmt":"2025-09-10T20:57:03","slug":"croseq-genomics","status":"publish","type":"page","link":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/croseq-genomics\/","title":{"rendered":"CROSEQ GENOMICS"},"content":{"rendered":"<div data-colibri-id=\"36-c1\" class=\"style-525 style-local-36-c1 position-relative\">\n  <!---->\n  <div data-colibri-component=\"section\" data-colibri-id=\"36-c2\" id=\"reusable-sections\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-530 style-local-36-c2 position-relative\">\n    <!---->\n    <!---->\n    <div class=\"h-section-grid-container h-section-fluid-container\">\n      <!---->\n      <div data-colibri-id=\"36-c3\" class=\"h-row-container gutters-row-lg-1 gutters-row-md-1 gutters-row-0 gutters-row-v-lg-1 gutters-row-v-md-1 gutters-row-v-1 style-531 style-local-36-c3 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-1 gutters-col-md-1 gutters-col-0 gutters-col-v-lg-1 gutters-col-v-md-1 gutters-col-v-1\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-1676-outer style-local-36-c4-outer\">\n            <div data-colibri-id=\"36-c4\" class=\"d-flex h-flex-basis h-column__inner h-ui-empty-state-container h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-1676 style-local-36-c4 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100\">\n                <!---->\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-1110-outer style-local-36-c5-outer\">\n            <div data-colibri-id=\"36-c5\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-1 h-px-md-1 h-px-1 v-inner-lg-1 v-inner-md-1 v-inner-1 style-1110 style-local-36-c5 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"36-c6\" class=\"h-global-transition-all h-heading style-1675 style-local-36-c6 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-1675 style-local-36-c6\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">INTERNATIONAL GENOME PROGRAMS<\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-1678-outer style-local-36-c7-outer\">\n            <div data-colibri-id=\"36-c7\" class=\"d-flex h-flex-basis h-column__inner h-ui-empty-state-container h-px-lg-1 h-px-md-1 h-px-1 v-inner-lg-1 v-inner-md-1 v-inner-1 style-1678 style-local-36-c7 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100\">\n                <!---->\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n  <div data-colibri-component=\"section\" data-colibri-id=\"36-c12\" id=\"custom\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-540 style-local-36-c12 position-relative\">\n    <!---->\n    <!---->\n    <div class=\"h-section-grid-container h-section-fluid-container\">\n      <!---->\n      <div data-colibri-id=\"36-c13\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-1233 style-local-36-c13 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-1234-outer style-local-36-c14-outer\">\n            <div data-colibri-id=\"36-c14\" class=\"d-flex h-flex-basis h-column__inner h-ui-empty-state-container h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-1234 style-local-36-c14 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100\">\n                <!---->\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-1235-outer style-local-36-c15-outer\">\n            <div data-colibri-id=\"36-c15\" class=\"d-flex h-flex-basis h-column__inner h-ui-empty-state-container h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-1235 style-local-36-c15 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100\">\n                <!---->\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n  <div data-colibri-component=\"section\" data-colibri-id=\"36-c16\" id=\"custom-2\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-543 style-local-36-c16 position-relative\">\n    <!---->\n    <!---->\n    <div class=\"h-section-grid-container h-section-boxed-container\">\n      <!---->\n      <div data-colibri-id=\"36-c17\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-544 style-local-36-c17 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-545-outer style-local-36-c18-outer\">\n            <div data-colibri-id=\"36-c18\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-545 style-local-36-c18 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"36-c19\" class=\"h-global-transition-all h-heading style-557 style-local-36-c19 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-557 style-local-36-c19\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">IGP (International Genome Programs) are designed to perform advanced clinical genome interpretation using large-scale datasets and sophisticated tools across multiple institutions. The overarching goal of these programs is to develop\n                      a systematic framework for interpreting the genomic landscape from whole genome sequencing (WGS) data to investigate the genetic etiology of disease. Using joint genome analysis of probands and unaffected family members (e.g., trio,\n                      quad), we investigate the genomic landscape and informative de novo and inherited genetic variants. These aggregated genomic datasets provide scientifically invaluable resources that can be used to map genome variation, reveal a\n                      spectrum of genetic variants with potential functional impact, and chart disease risk factors across diverse populations.<\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>INTERNATIONAL GENOME PROGRAMS IGP (International Genome Programs) are designed to perform advanced clinical genome interpretation using large-scale datasets and sophisticated tools across multiple institutions. The overarching goal of these programs is to develop a systematic framework for interpreting the genomic landscape from whole genome sequencing (WGS) data to investigate the genetic etiology of disease. Using [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/full-width-page.php","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-36","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/pages\/36","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/comments?post=36"}],"version-history":[{"count":21,"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/pages\/36\/revisions"}],"predecessor-version":[{"id":3936,"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/pages\/36\/revisions\/3936"}],"wp:attachment":[{"href":"https:\/\/ghazani-lab.bwh.harvard.edu\/index.php\/wp-json\/wp\/v2\/media?parent=36"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}